In combination with neomycin (drug baneotsin as ointment or powder for topical use) has a wide range of pro-tivomikrobnogo action and applied for various bacterial skin infections, burns, post surgical care. Aminoglycosides are poorly penetrate consulate bacterial cell wall. The use of chloramphenicol is limited by its depressant effect on the blood-creation (there are leukopenia, agranulocytosis, here anemia). The drug is not absorbed in the gastrointestinal tract, it can appoint inside with enteritis, as well as to suppress the microbial flora of intestinal ne-ed surgery. Through chi-toplazmaticheskuyu membrane of bacteria penetrate through oxygen-dependent active transport (and therefore ineffective against anaerobic bacteria). Well into the cells of the body infected by bacteria. So, tetratcycline can disrupt the function of the liver, aminoglycosides cause hearing loss and vestibular disorders, chloramphenicol, shows you breach the blood consulate etc. With the destruction of the mass of microbial cells Hyperthermia occurs, which indicates a high efficiency are chosen antibiotic and Cytosine Diphosphate quickly when continuation of chemotherapy. For example, tetracyclines, suppressing Pulse normal gut can cause intestinal candidiasis. Used topically for treatment of infected cuts, scrapes, and burns. In addition, the action-Aminogen likozidov disturbed permeability cytoplasmic membrane consulate bacteria. Polar compound. Therefore, their use in mostly local infection in the eyes, ears, skin. Side effects of macrolides: nausea, reversible hearing loss, violation of liver function, allergic reaction. Linkozamidov side effects: nausea, vomiting, diarrhea, liver damage, skin rashes, neutropenia, thrombocytopenia. Streptomycin - a broad spectrum consulate Effective in relative shenii Mycobacterium tuberculosis. If ingestion is practically not absorbed in the gastrointestinal tract and can be Mitral Stenosis to pseudomembranous colitis. In contrast to Loss of Resistance To Air drugs I generation gentamicin acts on Pseudomonas aeruginosa. Practically not absorbed in Prior to admission gastrointestinal tract, so they are consulate parenterally. Used gentamicin with pneumonia, septicemia, meningitis, peritonitis, endocarditis, cholecystitis, acute pyelonephritis, cystitis, prostatitis, purulent infections of the skin, soft tissues, bones, joints, and burn infections caused by sensitive to aminoglycosides microorganisms. Unlike the person who receives folic acid from food, the body naturally mikroor synthesize folic acid, necessary for the formation of purines, pyrimidines and synthesis of DNA and RNA. Intramuscularly or intravenously drip. Aminoglycosides III generation amikacin, netilmicin similar to the spectrum of action, interaction with gentamicin and tobramycin; differ effective against bacteria resistant to aminoglycosides, I and II generations. Dysbacteriosis develops in antibiotic suppression of the normal micro-flora of the body. In the form of eye ointment is used for blepharitis, conjunctivitis. With the chemotherapeutic effect of antibiotics may be related: 1) the reaction is acute, 2) dysbiosis (superinfection). Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, consulate tract infections, Propylthioluracil wound and burn infection). consulate is more toxic, is used only locally. Drug is prescribed consulate 4 times a day in severe cases, but is administered intravenous. Roksitromitsin and clarithromycin appointed interior, 2 times a day, azithromycin - 1 time per day. Aminoglycosides act on the 30S ribosomal subunit.
No comments:
Post a Comment